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Throughput-scalable manufacturing of SARS-CoV-2 mRNA lipid nanoparticle vaccines.
Shepherd SJ, Han X, Mukalel AJ, El-Mayta R, Thatte AS, Wu J, Padilla MS, Alameh MG, Srikumar N, Lee D, Weissman D, Issadore D, Mitchell MJ. Shepherd SJ, et al. Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e2303567120. doi: 10.1073/pnas.2303567120. Epub 2023 Aug 9. Proc Natl Acad Sci U S A. 2023. PMID: 37556502 Free PMC article.
In vivo bone marrow microenvironment siRNA delivery using lipid-polymer nanoparticles for multiple myeloma therapy.
Guimarães PPG, Figueroa-Espada CG, Riley RS, Gong N, Xue L, Sewastianik T, Dennis PS, Loebel C, Chung A, Shepherd SJ, Haley RM, Hamilton AG, El-Mayta R, Wang K, Langer R, Anderson DG, Carrasco RD, Mitchell MJ. Guimarães PPG, et al. Among authors: shepherd sj. Proc Natl Acad Sci U S A. 2023 Jun 20;120(25):e2215711120. doi: 10.1073/pnas.2215711120. Epub 2023 Jun 13. Proc Natl Acad Sci U S A. 2023. PMID: 37310997 Free PMC article.
Microfluidic generation of diverse lipid nanoparticle libraries.
R Hanna A, J Shepherd S, Issadore D, J Mitchell M. R Hanna A, et al. Among authors: j shepherd s. Nanomedicine (Lond). 2024 Jan 19. doi: 10.2217/nnm-2023-0345. Online ahead of print. Nanomedicine (Lond). 2024. PMID: 38240188 No abstract available.
High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models.
Xue L, Hamilton AG, Zhao G, Xiao Z, El-Mayta R, Han X, Gong N, Xiong X, Xu J, Figueroa-Espada CG, Shepherd SJ, Mukalel AJ, Alameh MG, Cui J, Wang K, Vaughan AE, Weissman D, Mitchell MJ. Xue L, et al. Among authors: shepherd sj. Nat Commun. 2024 Feb 29;15(1):1884. doi: 10.1038/s41467-024-45422-9. Nat Commun. 2024. PMID: 38424061 Free PMC article.
Rational design of anti-inflammatory lipid nanoparticles for mRNA delivery.
Zhang H, Han X, Alameh MG, Shepherd SJ, Padilla MS, Xue L, Butowska K, Weissman D, Mitchell MJ. Zhang H, et al. Among authors: shepherd sj. J Biomed Mater Res A. 2022 May;110(5):1101-1108. doi: 10.1002/jbm.a.37356. Epub 2022 Jan 25. J Biomed Mater Res A. 2022. PMID: 35076171 Free PMC article.
17 results